Dixon 2013.
Trial name or title | "Use of heparin to prevent lung microvascular thrombosis in patients administered aprotinin undergoing cardiac surgery for ischemic heart disease for ischemic heart disease" |
Methods | Phase II, RCT, blinded |
Participants | Patients 18 years or older undergoing elective cardiac surgery |
Interventions | Intervention: heparin intravenous infusion (18U/kg/hr) over the 3 hours prior to commencement of surgery Control: placebo (equivalent infusion of 5% dextrose with no active drug |
Outcomes | Primary outcome: evidence of microvascular thrombosis on lung biopsy taken at the end of cardiac surgery Secondary outcome: alveolar dead space |
Starting date | 2006 |
Contact information | barry.dixon@svhm.org.au |
Notes | Trial ID: ACTRN12606000328572. The study is not yet recruiting |