Skip to main content
. 2015 Jun 19;2015(6):CD009658. doi: 10.1002/14651858.CD009658.pub2

Dixon 2013.

Trial name or title "Use of heparin to prevent lung microvascular thrombosis in patients administered aprotinin undergoing cardiac surgery for ischemic heart disease for ischemic heart disease"
Methods Phase II, RCT, blinded
Participants Patients 18 years or older undergoing elective cardiac surgery
Interventions Intervention: heparin intravenous infusion (18U/kg/hr) over the 3 hours prior to commencement of surgery
Control: placebo (equivalent infusion of 5% dextrose with no active drug
Outcomes Primary outcome: evidence of microvascular thrombosis on lung biopsy taken at the end of cardiac surgery
Secondary outcome: alveolar dead space
Starting date 2006
Contact information barry.dixon@svhm.org.au
Notes Trial ID: ACTRN12606000328572. The study is not yet recruiting