Table 2.
Research and Surveillance Centre additional surveillance objectives that might be added to the World Health Organization mosaic framework.
| Additional RSCa objectives | RSC deliveryb | Completeness |
| PPIc | PPI is fundamentally important. We need the support of patients and the public for what we do. It is hard for us to fulfil our information governance responsibilities regarding informing patients and the public without strong PPI work. | Partial delivery: RSC and UKHSAd |
| Monitor bacterial infections | Primary and secondary bacterial infections are significant contributors to the burden of respiratory disease. Informing hospitals about these pressures is challenging without considering bacterial diseases. Our innovations include (1) POCTe for group A streptococcal infection and (2) urinary antigen tests to test for pneumococcus infection. We plan to improve the use of routinely collected bacteriology data. | Piloting by the RSC in collaboration with the UKHSA |
| POCT system-level evaluation | While we have evaluated POCT at the individual test level (mainly the sensitivity and specificity of specific virological tests), the RSC has the capability to evaluate the effectiveness of POCT at the system level. Outcomes could include: (1) antimicrobial stewardship, (2) use and effectiveness of antivirals, and (3) early intervention in high-risk individuals or populations. | Piloting by the RSC |
| Secured data governance | Our data governance portfolio, including the commissioning letter as described in the legal basis and governance framework for conducting sentinel surveillance, facilitates secure data use within the RSC. | Legal and national standards met by the RSC |
| Genomic surveillance resource | Our biomedical resource will link clinical data to virology sequencing data held in a publicly accessible resource. This will enable the linkage of clinical disease features and outcomes to the viral genomic sequence. | Partial delivery: RSC and UKHSA to complete this Wellcome Trust–funded project in 2024 |
aRSC: Research and Surveillance Centre.
bEach row is cumulative. Only new features are added in each row.
cPPI: patient and public involvement.
dUKHSA: UK Health Security Agency.
ePOCT: point-of-care testing.