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. 2024 Apr 17;7(4):e246865. doi: 10.1001/jamanetworkopen.2024.6865

Table 2. Events Occurring Within 6 Months of First Prescription of Guideline-Recommended Hypnotics.

Outcome Treatment group, No. (%) of patientsa
Eszopiclone (n = 34 050) Ramelteon (n = 14 523) Suvorexant (n = 37 547) Zolpidem (n = 135 492) Triazolam (n = 17 956) All (N = 239 568)
Monotherapy failure 4062 (11.9) 2193 (15.1) 4767 (12.7) 12 066 (8.9) 1690 (9.4) 24 778 (10.3)
Monotherapy discontinuation 24 857 (73.0) 10 468 (72.1) 27 538 (73.3) 105 138 (77.6) 13 622 (75.9) 181 623 (75.8)
Continuation for 6 mo 3627 (10.7) 1268 (8.7) 3564 (9.5) 12 915 (9.5) 1897 (10.6) 23 271 (9.7)
Censored 1504 (4.4) 594 (4.1) 1678 (4.5) 5373 (4.0) 747 (4.2) 9896 (4.1)
a

Percentages have been rounded and may not total 100.