Table 3.

Summary of statistical comparisons.

Figure	Comparison	Test	Value	Post-hoc
1b	Transcript	Kruskal-Wallis	P = 0.2827	n/a
1c	Protein	Kruskal-Wallis	P = 0.6821	n/a
2b	AIS length	One-way ANOVA	F(2,177) = 1.807, P = 0.1671	n/a
3b	Evoked neuronal excitability	Two-way ANOVA	F(2, 1548) = 141.6, p < 0.0001	Tukey’s
3c	Resting membrane potential	One-way ANOVA	F(2, 36) = 4.0005, P = 0.0269	Tukey’s
3d	AP threshold	One-way ANOVA	F(2, 39) = 4.487, P = 0.0176	Tukey’s
3e	AP half-width	One-way ANOVA	F(2, 34) = 7.678, P = 0.0018	Tukey’s
3f	AP Amplitude	One-way ANOVA	F(2, 36) = 3.115, P = 0.0565	Tukey’s
3g	Upstroke velocity	One-way ANOVA	F(2, 36) = 10.21, P = 0.0003	Tukey’s
3h	Downstroke velocity	One-way ANOVA	F(2, 36) = 7.495, P = 0.0019	Tukey’s
3i	fAHP	One-way ANOVA	F(2, 40) = 5.976, P = 0.0054	Tukey’s
3j	Input resistance	One-way ANOVA	F(2, 27) = 6.392, P = 0.0041	Tukey’s
4a	Open field total distance	One-way ANOVA	F(2,44) = 20.60, p < 0.0001	Tukey’s
4b	Open field 10-min bins	Two-way repeated measures ANOVA	F(2,44) = 19.11, p < 0.0001, Genotype; F (3.821,168.1) = 119.0, p < 0.0001, Time; F (10,220) = 0.6897, P = 0.7336, Interaction	Tukey’s
4c	Open field zone transitions	One-way ANOVA	F(2,44) = 4.86, P = 0.012	Tukey’s
4d	Open field-center time	One-way ANOVA	F(2,44) = 1.20, P = 0.31	n/a
5a	Flurothyl - MJ latency	Kruskal-Wallis	H(2) = 12.28, P = 0.0022	Dunn’s
5b	Flurothyl - GTCS latency	Kruskal-Wallis	H(2) = 35.83, p < 0.0001	Dunn’s
5c	Flurothyl – MJ-GTCS interval	Kruskal-Wallis	H(2) = 13.50, P = 0.0012	Dunn’s
5d	KA latency	Two-way repeated measures ANOVA	F(5,209) = 31.48, p < 0.0001, Genotype; F(5, 209) = 44.12, p < 0.0001, Racine Score; F (10, 209) = 4.921, p < 0.0001, Interaction	Tukey’s
5e	KA-survival	Mantel-Cox	p < 0.0001	n/a
7a	RMS	Two-way ANOVA	F(2,37) = 5.322, P = 0.0093	Tukey’s
7b	Cyclic frequency	Two-way ANOVA	F(2,37) = 3.548, P = 0.0389	Tukey’s
7c	Spike frequency	Kruskal-Wallis ANOVA	p < 0.0001	Dunn’s

n/a = not applicable.