Table 4.
EEG abnormalities in Kcnb1R306C mice.
| Genotype | Total hours (manually reviewed) | Select hours (spike counting) | Spike calculations. n = 3 sets of 6 h/mouse | ||
|---|---|---|---|---|---|
| Avg. RMS (uv) ± SD | Avg. cyclic frequency (Hz) ± SD | Avg. spike frequency (Hr−1) ± SD | |||
| WT | 117.4 | 18.0 | 9.5 ± 0.7 | 5.5 ± 0.1 | 3.4 ± 0.8 |
| 119.6 | 18.0 | 10.5 ± 1.4 | 5.0 ± 0.5 | 2.2 ± 1.9 | |
| 70.1 | 18.0 | 14.7 ± 0.5 | 5.2 ± 0.1 | 2.6 ± 1.2 | |
| 70.2 | 18.0 | 11.2 ± 0.9 | 5.4 ± 0.1 | 5.1 ± 2.8 | |
| 70.3 | 18.0 | 24.8 ± 0.2 | 4.9 ± 0.02 | 3.5 ± 2.0 | |
| 73.3 | 18.0 | 45.0 ± 2.6 | 4.5 ± 1.3 | 222.9 ± 294.2 | |
| C/+ | 72.2 | 18.0 | 18.5 ± 5.1 | 5.6 ± 0.6 | 17.5 ± 14.5 |
| 70.4 | 18.0 | 8.7 ± 0.4 | 5.3 ± 0.1 | 8.0 ± 3.6 | |
| 70.6 | 18.0 | 23.7 ± 0.6 | 4.8 ± 0.2 | 19.4 ± 7.6 | |
| 70.4 | 18.0 | 30.0 ± 10.2 | 4.6 ± 0.8 | 62.4 ± 43.4 | |
| 73.4 | 18.0 | 11.9 ± 4.5 | 4.6 ± 0.3 | 13.5 ± 4.4 | |
| 70.6 | 18.0 | 17.7 ± 2.3 | 4.5 ± 0.5 | 214.8 ± 170.3 | |
| C/C | 70.3 | 18.0 | 26.1 ± 18.1 | 4.2 ± 1.7 | 28.4 ± 9.8 |
| 76.2 | 18.0 | 20.4 ± 0.2 | 5.6 ± 0.1 | 37.7 ± 5.7 | |
| 72.3 | 18.0 | 43.4 ± 9.0 | 3.6 ± 0.8 | 61.3 ± 40.7 | |