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. 2015 Jul;43(7):1028–1036. doi: 10.1124/dmd.115.063388

Fig. 4.

Fig. 4.

Calculated differences for V-PYRRO/NO and V-PROLI/NO concentrations between inlet and outlet effluent samples following perfusion with 10 µM (A) and 50 µM compound (B). (C) Fraction of dose that was eliminated unchanged by the kidney. Values are expressed as the mean ± S.E.M. *P < 0.05; **P < 0.01 (n = 4 for isolated, perfused mouse liver experiments, and n = 7 for renal elimination evaluation).