Table 2.

Study outcomes and assessment procedures

Outcome	Procedure
Muscle Mass*	Whole-body DXA Scan
Fatigue	FACIT-Fatigue Questionnaire
Physical Function	PROMIS Physical Function Questionnaire
	Short Physical Performance Battery
Strength	Handgrip Strength Test
Independence	Katz Index of Independence in Activities of Daily Living
Insulin Sensitivity (HOMA-IR)	Calculated from measured fasting insulin & glucose**
Fat Mass	Whole-body DXA scan
Serum PSA	Blood Draw
cell-free DNA

*Primary outcome; **Fasting insulin and glucose assessment requires a blood draw