Table 4.
Endothelial function and vascular compliance data by category
| 5% or greater reduction in sedentary time | 0–4.99% reduction | Increase in sedentary time | P -values (time effect) | P -values (time × group interaction) | ||||
|---|---|---|---|---|---|---|---|---|
| ( N = 27) | ( N = 27) | ( N = 39) | ||||||
| Baseline | Week 12 | Baseline | Week 12 | Baseline | Week 12 | |||
| Baseline brachial diameter (mm) | 3.86±0.74 | 3.80±0.81 | 3.91±0.72 | 3.92±0.74 | 3.66±0.75 | 3.68±0.76 | 0.76 | 0.63 |
| Baseline peak shear (dynes/ cm 2 ) | 43±14 | 41±14 | 42±12 | 39±12 | 44±14 | 43±13 | 0.09 | 0.9 |
| Hyperemic peak shear (dynes/ cm 2 ) a | 71±20 | 75±36 | 74±24 | 71±20 | 78±21 | 73±24 | 0.53 | 0.35 |
| Nitroglycerin- mediated dilation(%) b | 19.9±6.1 | 19.1±6.3 | 21.0±8.0 | 17.90±7.6 | 22.1±5.7 | 19.7±5.9 | 0.05 | 0.66 |
| Carotid- femoral pulse wave velocity (cm/sec) c | 9.6±2.3 | 9.1±2.5 | 9.9±1.6 | 9.9±1.5 | 9.3±2.1 | 9.2±1.9 | 0.31 | 0.56 |
| Augmentation index d | 28.3±8.0 | 25.48±7.1 | 24.30±8.5 | 25.2±17.0 | 28.4±10.0 | 25.8±9.6 | 0.19 | 0.34 |
| Aortic systolic blood pressure d | 120±13 | 121±15 | 120±10 | 120±13 | 119±13 | 118±14 | 0.81 | 0.63 |
| Aortic diastolic blood pressure d | 69±8 | 69±9 | 73±7 | 72±8 | 68±7 | 69±8 | 0.91 | 0.71 |
a N = 26, 27, and 38 for category groups 1, 2, and 3, respectively. bN = 21, 18, and 25 for category groups 1, 2, and 3, respectively. cN = 24, 23, and 23 for category groups 1, 2, and 3, respectively. dN = 27, 27, and 36 for category groups 1, 2, and 3, respectively.