Fig 3.

Physical clustering and domain fusion link the YtqA subgroup with mnm⁵s²U synthesis. (A) Examples of fusions between proteins involved in the last steps of mnm⁵s²U synthesis. Protein domains are color-coded MnmC1 (dark green), MnmC2 (light green), MnmM (light gray), and YtqA (dark gray). The number of examples of such fusions present in the InterPro database is given between brackets; see Data S4A for the complete list of YtqA/MnmM, MnmC1/MnmM, and YtqA/MnmC2 fusions. (B) Examples of physically clustered ytqA (dark gray) and mnmM (light gray) in Gram-positive species. Data extracted from the SSN analysis performed for Fig. 4.