TABLE 3.

Antibody response in mice immunized with pV1J-CDV-F

DNA and route	Dose (μg)	Wk of sampling (no. of inoculations)	Level (mean ± SD; ng/ml) of:
			IgG1	IgG2a
pV1J-CDV-F in PBS, i.m.	100	3	690 ± 230	1,670 ± 657
		7	213 ± 100	950 ± 480
	20	3	687 ± 530	1,009 ± 574
		7	448 ± 743	312 ± 187
pV1J-CDV-F, gene gun	2	6 (1)	5,345 ± 2,400	8,232 ± 1,930
		6 (2)	15,400 ± 3,467	10,300 ± 3,420
		15 (1)	9,000 ± 990	4,000 ± 770
		15 (2)	21,000 ± 6,600	14,000 ± 4,000
	0.5	6 (1)	2,000 ± 1,000	2,500 ± 485
		6 (2)	8,500 ± 5,480	13,500 ± 7,200
		15 (1)	5,200 ± 1,344	3,000 ± 1,484
		15 (2)	13,600 ± 6,500	11,000 ± 4,000
	0.1	6 (1)	2,300 ± 264	1,461 ± 840
		6 (2)	3,000 ± 660	4,600 ± 1,250
		15 (1)	—a	600 ± 210
		15 (2)	1,600 ± 655	1,900 ± 1,153

^a—, level of <1 ng/ml.