Table 1b:
Waitlisted Liver Cohort Characteristics by Era
| Characteristic | Waitlist Era | Total (N=121,298) | P value | ||
|---|---|---|---|---|---|
| Era 1: 2007 – 2010 (N=38,575) | Era 2: 2011 – 2014 (N=39,656) | Era 3:2015–2018 (N=43,067) | |||
| Race | <0.0011 | ||||
| White | 27,203 (70.5%) | 27,778 (70.0%) | 29,920 (69.5%) | 84,901 (70.0%) | |
| Black or African American | 3,529 (9.1%) | 3,699 (9.3%) | 3,578 (8.3%) | 10,806 (8.9%) | |
| American Indian or Alaska Native | 257 (0.7%) | 300 (0.8%) | 438 (1.0%) | 995 (0.8%) | |
| Asian | 1,800 (4.7%) | 1,716 (4.3%) | 1,887 (4.4%) | 5,403 (4.5%) | |
| Native Hawaiian or Other Pacific Islander | 67 (0.2%) | 74 (0.2%) | 76 (0.2%) | 217 (0.2%) | |
| Hispanic / Latino | 5,571 (14.4%) | 5,925 (14.9%) | 6,941 (16.1%) | 18,437 (15.2%) | |
| Multi-Racial | 148 (0.4%) | 164 (0.4%) | 227 (0.5%) | 539 (0.4%) | |
| Sex | <0.0011 | ||||
| Female | 13,710 (35.5%) | 13,976 (35.2%) | 15,811 (36.7%) | 43,497 (35.9%) | |
| Male | 24,865 (64.5%) | 25,680 (64.8%) | 27,256 (63.3%) | 77,801 (64.1%) | |
| Calculated Candidate Age at Listing | <0.0012 | ||||
| Mean (SD) | 53.6 (10.2) | 55.1 (10.2) | 55.6 (10.9) | 54.8 (10.5) | |
| Median | 55.0 | 57.0 | 58.0 | 57.0 | |
| Q1, Q3 | 49.0, 60.0 | 51.0, 62.0 | 50.0, 64.0 | 50.0, 62.0 | |
| Range | (18.0–81.0) | (18.0–82.0) | (18.0–79.0) | (18.0–82.0) | |
| BMI at listing (kg/m2) | <0.0012 | ||||
| Missing | 244 (0.6%) | 127 (0.3%) | 151 (0.4%) | 522 (0.4%) | |
| Mean (SD) | 28.5 (5.7) | 28.8 (5.8) | 29.1 (6.0) | 28.8 (5.9) | |
| Median | 28.0 | 28.0 | 28.0 | 28.0 | |
| Q1, Q3 | 24.0, 32.0 | 25.0, 32.0 | 25.0, 33.0 | 25.0, 32.0 | |
| Range | (15.0–59.0) | (15.0–60.0) | (15.0–60.0) | (15.0–60.0) | |
| BMI of candidate at listing (kg/m2) | <0.0011 | ||||
| Missing | 244 (0.6%) | 130 (0.3%) | 156 (0.4%) | 530 (0.4%) | |
| [15–19) | 627 (1.6%) | 531 (1.3%) | 579 (1.3%) | 1,737 (1.4%) | |
| [19–25) | 9,117 (23.8%) | 9,024 (22.8%) | 9,420 (22.0%) | 27,561 (22.8%) | |
| [25–30) | 13,611 (35.5%) | 14,046 (35.5%) | 14,782 (34.4%) | 42,439 (35.1%) | |
| [30–40) | 13,440 (35.1%) | 14,065 (35.6%) | 15,637 (36.4%) | 43,142 (35.7%) | |
| [40–60) | 1,536 (4.0%) | 1,860 (4.7%) | 2,493 (5.8%) | 5,889 (4.9%) | |
| First SRTR MELD given | <0.0012 | ||||
| Mean (SD) | 17.4 (8.7) | 17.7 (8.9) | 18.1 (9.2) | 17.8 (9.0) | |
| Median | 15.0 | 15.0 | 16.0 | 15.0 | |
| Q1, Q3 | 11.0, 21.0 | 11.0, 22.0 | 11.0, 23.0 | 11.0, 22.0 | |
| Range | (6.0–40.0) | (6.0–40.0) | (6.0–40.0) | (6.0–40.0) | |
| Diabetes Status | <0.0011 | ||||
| Missing | 549 (1.4%) | 158 (0.4%) | 89 (0.2%) | 796 (0.7%) | |
| No | 28,214 (74.2%) | 28,647 (72.5%) | 29,992 (69.8%) | 86,853 (72.1%) | |
| Yes | 9,812 (25.8%) | 10,851 (27.5%) | 12,986 (30.2%) | 33,649 (27.9%) | |
| Hypertension | <0.0011 | ||||
| Missing | 10,420 (27.0%) | 8,661 (21.8%) | 41,503 (96.4%) | 60,584 (49.9%) | |
| No | 20,698 (73.5%) | 21,185 (68.3%) | 1,039 (66.4%) | 42,922 (70.7%) | |
| Yes | 7,457 (26.5%) | 9,810 (31.7%) | 525 (33.6%) | 17,792 (29.3%) | |
| States by Expansion Year | <0.0011 | ||||
| Missing | 191 (0.5%) | 236 (0.6%) | 169 (0.4%) | 596 (0.5%) | |
| Initial expansion | 20,364 (53.1%) | 20,803 (52.8%) | 22,234 (51.8%) | 63,401 (52.5%) | |
| Later expansion | 5,024 (13.1%) | 4,774 (12.1%) | 5,025 (11.7%) | 14,823 (12.3%) | |
| Late/No expansion | 12,996 (33.9%) | 13,843 (35.1%) | 15,639 (36.5%) | 42,478 (35.2%) | |
1
Chi-Squared
2
ANOVA F-Test