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. 2024 Apr 18;19(4):e0298080. doi: 10.1371/journal.pone.0298080

Fig 4. Rabbit mAbs against pS409/410-TDP-43 detect the pathological accumulation of phosphorylated TDP-43 in FTLD-TDP brain tissues.

Fig 4

(A) Immunoblot analysis of urea-soluble fractions from the frontal cortex of FTLD-TDP patients and normal controls using the indicated rabbit mAbs. (B) MSD analysis of phosphorylated TDP-43 protein levels in urea-soluble fractions from the frontal cortex of FTLD-TDP patients and normal controls using the indicated rabbit mAbs (n = 4−5 per group). Data shown as the mean ± SEM. ** (left to right) P  =  0.0050, 0.0091 and 0.0075, unpaired two-tailed t-test.