Table 2.

Ribosome drop-off rates estimated by Ribofilio (bin-size = 50)

Dataset	Drop-off rate per bin (rb)	Drop-off rate per codon (rc)	RMSE		SE	CI	p-value
D1	0.0051	0.0003	0.0143	0.4907	0.0006	r b ± 0.0011	<0.00001
D2	0.0102	0.0006	0.025	0.6887	0.0007	r b ± 0.0013	<0.00001
D3	0.0100	0.0006	0.0762	0.4104	0.0011	r b ± 0.0021	<0.00001
D4	0.0073	0.0004	0.0282	0.4993	0.0003	r b ± 0.0006	<0.00001
D5	0.0057	0.0003	0.4843	0.0341	0.0021	r b ± 0.0041	0.0038
D6	0.0053	0.0003	0.3147	0.0462	0.0019	r b ± 0.0038	0.0029
D7	0.0079	0.0005	0.5336	0.0594	0.0027	r b ± 0.0053	0.0016
D8	0.0077	0.0005	0.4188	0.0709	0.0027	r b ± 0.0052	0.0020

Column 1: Dataset ID (Table 1); the datasets used as reference in the comparative analysis (S. cerevisiae cultured in standard conditions) are highlighted in bold. Column 2: Drop-off rate per bin (rb). Column 3: Drop-off rate per codon (rc). Column 4: RMSE. Column 5: coefficient of determination (R2). Column 6: Standard Error Estimate (SE).Column 7: Confidence Interval 95%. Column 8: P-value resulting from the t-test (null hypothesis: r_b = 0) performed according to Equation (6).