Table 2. Comparison of mean frequencies of micronuclei in women with and without HPV infection, in relation to risk factors for cervical cancer.
| Factor | HPV | No HPV | ||
|---|---|---|---|---|
| n | Micronucleus frequency (mean ± SD) | n | Micronucleus frequency (mean ± SD) | |
| Alcoholic * | 25 | 9.6 ± 8.1 | 6 | 2.5 ± 1.1 |
| Smoker * | 32 | 10.0 ± 7.8 | 15 | 1.7 ± 1.8 |
| Infectious agents for vaginitis * | 22 | 9.7 ± 8.2 | 9 | 4.0 ± 4.4 |
| Cytology with inflammation | 47 | 13.2 ± 10.7 | 18 | 10.7 ± 1.05 |
| CIN * | 53 | 14.2 ± 18.9 | 3 | 4.6 ± 4.9 |
| Oral contraceptive * | 30 | 9.8 ± 9.6 | 25 | 1.7 ± 2.2 |
*
P < 0.0001, for all data in comparison with no HPV; HPV = human papillomavirus; CIN = cervical intraepithelial neoplasia.