Figure 5.
Assessment of decellularized vascular grafts in vivo using non-invasive ultrasound. (A) Ultrasound spectral analysis of the carotid artery and jugular vein before and after transplantation of decellularized vascular grafts. The appearance of AVG-specific spectral patterns in the carotid artery and jugular vein after transplantation indicates successful modeling. (B) Color Doppler blood flow imaging and ultrasound spectrum of decellularized vascular grafts. (C) Evaluation of changes in the lumen size of the carotid artery and jugular vein. (D) Statistical analysis of the area and relative area of the carotid artery after transplantation (P < 0.0001, ANOVA; Day 0, Day 7, Day 21 and Day 42, n = 5; 1 year, n = 3). (E) Statistical analysis of the area and relative area of the jugular vein after transplantation (P < 0.0001, ANOVA; Day 0, Day 7, Day 21, and Day 42, n = 5; 1 year, n = 3).