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. 2024 Apr 18;15:3361. doi: 10.1038/s41467-024-47679-6

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Survival probability for recipients transplanted with 10GE renal xenografts. One recipient with high levels of preformed antibody to source pig 10GE cells (denoted as “High risk”) hyperacutely rejected graft. The remaining five recipients (denoted as “Low risk” for hyperacute graft loss) lost their grafts on POD165, POD252, POD285, and POD337. b Serum creatinine levels among these five recipients remained within the normal range until the development of irreversible graft failure.