FIG. 2.
Virus titers following i.p. WSN virus inoculation of STAT1−/− mice. Four STAT1−/− and three WT mice were injected i.p. with 107 PFU of WSN virus. Animals were sacrificed at day 4 postinoculation when the mutant animals showed signs of illness. Viral titers of tissue homogenates were determined by plaque assay in MDCK cells and are expressed as PFU/gram of tissue. Virus titers for each tissue are shown for each of the STAT1−/− animals. No virus could be detected in samples obtained from three WT animals.