Fig. 2.

Diverse cancer hallmarks targeted by repurposed non-oncology drugs. Repurposed non-oncology candidates have shown great promise against cancer by targeting different hallmarks of cancer including sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, activating invasion and metastasis, genome instability and mutation, tumor-promoting inflammation, reprogramming energy metabolism, evading immune destruction, unlocking phenotypic plasticity, non-mutational epigenetic regulation, polymorphic microbiomes, and senescent cells. This figure was created with Biorender.com