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. 2024 Apr 5;11:1341809. doi: 10.3389/fmed.2024.1341809

Table 3.

Factors associated with IBS in human medicine students, in simple and multiple regression analysis.

Characteristics Irritable Bowel Syndrome
Simple regression Multiple regression
RP 95% CI p* RP 95% CI p*
Age (years)* 0.88 0.79–0.97 0.015 0.91 0.83–0.99 0.028
Sex
Female Ref. Ref.
Male 0.52 0.34–0.81 0.004 0.85 0.61–1.18 0.335
Frequent alcohol consumption
No Ref.
Yes 1.32 0.45–3.90 0.608
Frequent tobacco use
No Ref.
Yes 1.06 0.21–5.38 0.940
Exhaustion from career activities
Never/almost never Ref.
Sometimes 1.35 0.33–5.46 0.676
Almost always/always 1.23 0.33–4.51 0.757
Regular exercise
No Ref.
Yes 1.26 0.90–1.76 0.185
Parents’ condition
Living together Ref.
Single 1.25 0.86–1.82 0.245
Family member diagnosed with IBS
No Ref.
Yes 1.40 0.72–2.71 0.317
Current housing
Parents’ house Ref.
Own house 0.49 0.17–1.39 0.179
Apartment rental 0.98 0.44–2.16 0.952
Depression
No Ref.
Yes 6.30 2.59–15.33 <0.001 3.63 1.26–10.49 0.017
Anxiety
No Ref.
Yes 4.07 1.63–10.13 0.003 1.59 0.71–3.57 0.264
Stress
No Ref.
Yes 1.95 0.78–4.86 0.154
BMI (Body Mass Index)
Normal Ref.
Overweight 0.68 0.31–1.49 0.336
Obesity 0.37 0.06–2.35 0.295
Hours of sleep
<8 h/day Ref.
≥8 h/day 0.67 0.35–1.35 0.229
Eating behavior disorder
No Ref.
Yes 2.32 1.70–3.18 <0.001 1.57 1.01–2.43 0.044

*P values obtained with Generalized Linear Models (GLM), Poisson family, log link function, robust variance, cluster by academic year.