Table 1.

PICO Model.

Population	Females above the age of 18 years diagnosed with PCOS using Rotterdam criteria
Intervention	Any form of intermittent fasting regimen such as time-restricted eating (TRE), alone or associated with pharmacological therapy, exercise, and weight loss. To include 16:8 method, 18:6 method, 5:2 diet, alternate day fasting, intermittent fasting, Ramadan model of intermittent fasting, or other suitable religious intermittent fasting regimens
Comparator	Comparison to the usual ad libitum diet or no dietary or non-fasting intervention, standard treatment-as-usual, and pharmacological therapy
Outcomes	Any PCOS metabolic, hormonal, inflammatory, or anthropometric markers including insulin levels, C-peptide concentrations, glucagon, insulin-like growth factor 1 (IGF-1), glycated hemoglobin (HbA1c), homeostatic model assessment for insulin resistance (HOMA-IR), fasting blood glucose, oral glucose tolerance test (OGTT), lipid profile such as and serum lipid profile parameters, low-density lipoprotein (LDL), high-density lipoprotein (HDL).; hormonal markers such as sex hormone binding globulin (SHBG), follicular stimulating hormone (FSH), luteinizing hormone (LH)