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. 2024 Mar 20;55(2):383–390. [Article in Chinese] doi: 10.12182/20240360105

表 3. ROC analysis of interferon efficacy according to the serum HBsAg and HBV pgRNA levels in different populations.

不同人群血清HBsAg和HBV pgRNA水平判断干扰素疗效的ROC分析

Group Index AUC 95% CI Optimal cut-off value Sensitivity/% Specificity/% P
 AUC: area under thecurve; CI: confidence interval.
Previously treated HBsAg 0.80 0.7423-0.8615 244.60 IU/mL 77.78 72.39 <0.0001
HBV pgRNA 0.58 0.4586-0.7024 3955.00 copies/mL 77.78 42.13 0.2606
Initial treatment HBsAg 0.74 0.6283-0.8604 934.40 IU/mL 100.00 50.85 0.0079
HBV pgRNA 0.96 0.9042-1.0000 1340.00 copies/mL 94.74 88.89 <0.0001