Table 2. Results of the safety assessment parameters.
Each value represents the mean±SD; n=32 for the SIVI (Passiflora incarnata extract) group and n=33 for the placebo group.
RBC: red blood cell; WBC: white blood cell; ESR: erythrocyte sedimentation rate; AST: aspartate aminotransferase; ALT: alanine aminotransferase; ALP: alkaline phosphatase; BUN: blood urea nitrogen
| Safety parameters | SIVI (Passiflora incarnata extract) group | Placebo group | ||
| Baseline | Day 30 | Baseline | Day 30 | |
| RBC (×106 cells/µL) | 4.31±0.56 | 4.32±0.57 | 4.36±0.49 | 4.44±0.52 |
| WBC (cells/mm3) | 6381.25±1839.6 | 6278.13±1371.5 | 6824.24±1620.8 | 6318.18±1002.3 |
| Haemoglobin (g/dL) | 12.79±2.13 | 12.72±2.06 | 12.68±1.69 | 12.71±1.53 |
| Platelets (×105 cells/mm3) | 2.73±0.76 | 2.63±0.71 | 2.79±0.58 | 2.82±0.68 |
| ESR (mm/hour) | 17.94±12.02 | 15.06±12.07 | 21.12±18.54 | 18.12±15.47 |
| Total bilirubin (mg/dL) | 0.77±0.23 | 0.74±0.22 | 0.75±0.26 | 0.74±0.23 |
| Direct (mg/dL) | 0.25±0.07 | 0.24±0.09 | 0.24±0.11 | 0.26±0.11 |
| Indirect (mg/dL) | 0.52±0.17 | 0.50±0.17 | 0.51±0.20 | 0.48±0.18 |
| AST (U/L) | 19.22±6.07 | 21.27±6.29 | 21.06±5.69 | 20.02±5.42 |
| ALT (U/L) | 28.79±12.46 | 28.82±10.62 | 30.81±10.54 | 28.24±11.37 |
| ALP (U/L) | 104.37±36.28 | 99.66±31.07 | 105.50±42.20 | 102.89±36.20 |
| Total proteins (g/dL) | 7.06±0.31 | 7.04±0.37 | 7.07±0.32 | 7.03±0.40 |
| Serum albumin (g/dL) | 4.04±0.45 | 4.05±0.35 | 3.91±0.50 | 3.93±0.34 |
| Serum creatinine (mg/dL) | 0.98±0.17 | 0.95±0.16 | 0.94±0.15 | 0.91±0.14 |
| BUN (mg/dL) | 10.33±2.34 | 10.53±2.77 | 10.08±2.52 | 9.93±2.68 |
| Fasting blood sugar (mg/dL) | 85.36±13.00 | 86.58±11.07 | 93.00±25.04 | 88.63±15.57 |