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. 2024 Apr 18;31:39. doi: 10.1186/s12929-024-01026-5

Table 1.

Distribution of disease severity, anti-ACE2 autoantibody and CR antibody positive rate in COVID-19 patients with vaccination (Vac) or without (UnVac)

Demographic UnVac (n = 31) Vac (n = 89) P valuea
Disease severity  < 0.0001
 Mild 4 (12.9%) 63 (70.8%)
  Positive for Anti-ACE2 autoAb 1 (25%) 7 (11.1%) ns
  Positive for CR Ab 0 1 (1.6%) ns
 Moderate/Severe 27 (87.1%) 26 (29.2%)
  Positive for Anti-ACE2 autoAb 18 (66.7%) 7 (26.9%) 0.058
  Positive for CR Ab 9 (33.3%) 1 (3.8%) 0.011

Abbreviation: ns not significant

aThe Fisher exact test was used to determine the P values