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. 2024 Apr 18;18(1):76. doi: 10.1186/s13065-024-01178-3

Table 1.

Validation of pharmacophore model by GH score

NO Parameters Model assessment
1 Total molecules in database (D) 1468
2 Total number of actives in database (A) 150
3 Total hits (Ht) 8
4 Active hits (Ha) 6
5 % Yield of actives[(Ha/Ht) × 100] 75
6 % Ratio of actives [(Ha/A) × 100] 4
7 Enrichment factor (E) [(Ha × D)/(Ht × A) 7
8 False negatives [AHa] 144
9 False positives [HtHa] 2
10 Goodness of hit score (GH) 0.76