Fig. 4.

Anlotinib increases the intratumoral myeloid cells, including DC and non–M2-like macrophages. a Representative images of the gating strategy for defining myeloid cell (CD11b⁺) tumor infiltration (left) and the percentages in TIL (right). b Flow cytometry analysis of MDSC (CD11b⁺Gr-1⁺) and APC (CD11b⁺CD11c⁺CD86⁺) in TIL. c Percentages of M2-like TAM (CD206⁺). Results are the means ± SEM, n = 5, one-way ANOVA. *p < 0.05, **p < 0.01