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. 2024 Apr 4;15:1367253. doi: 10.3389/fimmu.2024.1367253

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Copyright © 2024 Zhang, Liu, Zhang, Wang, Xu, Zhao, Xiang, Wu, Yang, Chen, Guo and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Detection of M. bovis HB0801 and BoHV-1 HB06 shedding after challenge. Nasal swabs of calves immunized with different antigenic ratios were collected every day. (A) Nasal swabs from groups challenged with M. bovis HB0801. (B) Nasal swabs from groups challenged with BoHV-1 HB06. (C) Trigeminal nerve samples from groups challenged with BoHV-1 HB06.