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. 2024 Apr 19;15:109. doi: 10.1186/s13287-024-03729-w

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Comparative analysis of patient-reported outcomes using the medical outcome study 36-item short form survey and the EuroQol 5 dimension 5 level dimensions at 6 and 12 months. A UC-MSCs versus placebo groups are visualized as radar chart. Each of the eight domains is scored on a scale from 0 to 100, with a higher score indicating better health and less impact of health on usual roles. In this radar chart, the central point represents a score of 0, while the outermost boundary corresponds to a score of 100. B and C Bar chart representation depicting the EQ-5D variables at 6 months (B) and at 12 months (C). At the 6-month assessment, 11 patients from the UC-MSCs group and 13 from the placebo group were evaluated (24 patients in global cohort). At the 12-month mark, 7 patients from the UC-MSCs group and 12 from the placebo group were assessed (19 patients in global cohort). EQ-5D EuroQol 5 Dimension 5 Level. M month. UC-MSCs umbilical cord-derived mesenchymal stromal cells. SF-36 36-Item Short Form Survey