Table 2.

Reported serious adverse events after day 28 up to 12 months of follow-up post-hospital discharge

	Group	Type of reaction/event	Relatedness of study to reaction/event	Outcome of reaction/event	Investigator’s comments
Patient 1 (event 1)	UC-MSCs	Coma	No	Death	No causality regarding this event
Patient 1 (event 2)	UC-MSCs	Terminal extubation	No	Death	No causality regarding this event
Patient 2	UC-MSCs	Septic shock	No	Death	Event is related to disease progression (ARDS associated to COVID-19)
Patient 3	Placebo	Multiple organ failure	No	Death	Event is related to disease progression (ARDS associated to COVID-19)