Table 3.
Pre-medication | Induction | Maintenance | Reversal | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Animal ID | Diaz (mg/kg) | Midaz (mg/kg) | Meper (mg/kg) | Midaz (mg/kg) | Propofol (mg/kg) | Sevo (FE%) | Midaz (mg/kg) | Meper (mg/kg) | Atrac (mg/kg) | Fluma (mg/kg) | Nalox (mg/kg) | Naltrex (mg/kg) |
Tt-1a* | - | 0.08 | 0.10 | 0.02 | 2.30 | 1.8–2.0 | - | - | - | 0.02 | 0.02 | - |
Tt-2 | - | 0.08 | 0.10 | 0.02 | 2.00 | 1.8–2.0 | - | - | - | 0.02 | 0.01 | - |
Tt-3 | 0.3 | 0.10 | 0.20 | 0.02 | 3.43 | 1.8–2.0 | - | - | - | 0.03 | 0.02 | 0.05 |
Tt-1b* | - | 0.10 | 0.20 | 0.02 | 4.89 | 1.8–2.0 | - | - | - | 0.02 | 0.04 | - |
Tt-5 | 0.08 | 0.10 | 0.10 | 0.02 | 1.73 | 1.8–2.0 | 0.04 | 0.1 | - | 0.02 | - | 0.05 |
Tt-6 | - | 0.08 | 0.10 | 0.02 | 2.00 | 1.8–2.0 | 0.03 | 0.1 | - | 0.02 | 0.01 | - |
Tt-7 | - | 0.12 | 0.10 | 0.02 | 2.91 | 1.8–2.0 | - | - | - | 0.04 | - | 0.10 |
Tt-8 | - | 0.08 | 0.10 | 0.02 | 3.02 | 1.8–2.0 | 0.06 | 0.1 | - | 0.02 | - | 0.15 |
Tt-9 | - | 0.10 | 0.10 | 0.02 | 2.42 | 1.8–2.0 | - | - | - | 0.02 | 0.02 | 0.15 |
Tt-10 | - | 0.08 | 0.10 | 0.02 | 2.25 | 1.8–2.0 | 0.12 | - | 0.9 | 0.05 | 0.02 | 0.20 |
Mean doses | 0.19 | 0.09 | 0.12 | 0.02 | 2.70 | 1.8–2.0 | 0.06 | 0.1 | 0.9 | 0.03 | 0.02 | 0.12 |
Overall dose means shown on the bottom row. Diaz, diazepam; Midaz, midazolam; Meper, meperidine; Sevo, sevoflurane; Atrac, atracurium; Fluma, flumazenil; Nalox, naloxone; Naltrex, naltrexone. *Denotes same female dolphin anesthetized on two separate occasions.