Table 1.
Demographic characteristics of lung adenocarcinoma patients in the discovery dataset. Independent-sample analysis involved 328 tumor tissues and 52 unrelated normal tissues; paired-sample analysis was performed on 57 paired tumor and normal tissues. Age, gender, race and smoking status were adjusted to detect DEGs in the independent-sample design
| Characteristics | Independent-sample design (N = 380) | Paired-sample design (N = 57) |
|---|---|---|
| Median age (years) | 66 | 66 |
| Gender, n (%) | ||
| Male | 167 (43.9) | 33 (57.9) |
| Female | 213 (56.1) | 24 (42.1) |
| Race, n (%) | ||
| Caucasian | 346 (91.1) | 53 (93.0) |
| Asian | 7 (1.8) | / |
| African | 26 (6.8) | 4 (7.0) |
| Indian | 1 (0.3) | / |
| Clinical stage, n (%) | ||
| I | 213 (56.1) | 29 (50.9) |
| II | 89 (23.4) | 13 (22.8) |
| III | 60 (15.8) | 13 (22.8) |
| IV | 18 (4.7) | 2 (3.5) |
| Smoking status, n (%) | ||
| Nona | 60 (15.8) | 7 (12.3) |
| Ref-ndb | 2 (0.5) | / |
| Ref < 15c | 134 (35.3) | 21 (36.8) |
| Ref > 15d | 92 (24.2) | 16 (28.1) |
| Cure | 92 (24.2) | 7 (12.3) |
| Missing information | / | 6 (10.5) |
aLifelong Nonsmoker
bCurrent reformed smoker, duration not specified
cCurrent reformed smoker for < or = 15 years
dCurrent reformed smoker for > 15 years
eCurrent smoker