Table 2.

Cox univariate and multivariate analysis of prognostic parameters for OS and PFS in patients with RCC (n = 83)

Prognostic parameter	Univariate analysis			Multivariate analysis
	HR	95% CI	P value	HR	95% CI	P value
Overall survival
Stage (I, II vs III, IV)	6.083	1.346–27.49	0.019	3.102	0.630–15.260	0.164
Grade (1, 2 vs 3)	2.917	0.773–11.010	0.114	2.149	0.544–8.483	0.275
CD8 (low vs high)	2.717	0.835–8.841	0.097
Foxp3 (low vs high)	1.535	0.511–4.609	0.445
PD-L1 (low vs high)	1.783	0.582–5.460	0.311
PD-L2 (low vs high)	1.034	0.318–3.360	0.955
B7-H4 (low vs high)	1.894	0.636–5.640	0.251
Galectin-9 (low vs high)	4.150	1.357–12.690	0.013	4.025	1.157–14.000	0.029
Progression-free survival
Stage (I, II vs III, IV)	12.54	3.790–41.490	< 0.001	9.871	2.858–34.090	< 0.001
Grade (1, 2 vs 3)	4.077	1.706–9.743	0.002	2.117	0.850–5.273	0.107
CD8 (low vs high)	1.527	0.744–3.133	0.248
Foxp3 (low vs high)	1.354	0.646–2.835	0.422
PD-L1 (low vs high)	0.857	0.367–1.997	0.720
PD-L2 (low vs high)	0.897	0.396–2.030	0.794
B7-H4 (low vs high)	2.664	1.267–5.600	0.010	2.538	1.150–5.603	0.021
Galectin-9 (low vs high)	1.376	0.639–2.966	0.415

HR hazard ratio, CI confidence interval