Table 3.
Correlations among CD19+, CD4+ and CD8+ cells expressing Tim-3, PD-1, and CCR5
| Cells | Tim-3+ CD19+ (%) | Tim-3+ CD4+ (%) | Tim-3+ CD8+ (%) | PD-1+CD19+ (%) | PD-1+CD4+ (%) | PD-1+CD8+ (%) | CCR5+CD19+ (%) | CCR5+CD4+ (%) | CCR5+CD8+ (%) |
|---|---|---|---|---|---|---|---|---|---|
| Tim-3+ CD19+ (%) | – |
r = 0.17 p value = 0.06 |
r = 0.06 p value = 0.3 |
r = 0.2 p value = 0.03 |
r = 0.2 p value = 0.03 |
r = − 0.02 p value = 0.4 |
r = − 0.1 p value = 0.2 |
r = − 0.2 p value = 0.01 |
r = 0.2 p value = 0.04 |
| Tim-3+ CD4+ (%) |
r = 0.17 p value = 0.06 |
– |
r = 0.7 p value = < 0.0001 |
r = 0.6 p value < 0.0001 |
r = 0.6 p value < 0.0001 |
r = 0.4 p value < 0.0001 |
r = − 0.04 p value = 0.4 |
r = − 0.2 p value = 0.02 |
r = − 0.4 p value < 0.0001 |
| Tim-3+ CD8+ (%) |
r = 0.06 p value = 0.3 |
r = 0.7 p < 0.0001 |
– |
r = 0.3 p value = 0.004 |
r = 0.3 p value = 0.004 |
r = 0.3 p value = 0.01 |
r = 0.17 p value = 0.07 |
r = − 0.1 p value 0.2 |
r = − 0.3 p value = 0.004 |
| PD-1+CD19+ (%) |
r = 0.2 p value = 0.03 |
r = 0.6 p value < 0.0001 |
r = 0.3 p value = 0.004 |
– |
r = 1 p < 0.0001 |
r = 0.6 p value < 0.0001 |
r = − 0.2 p value = 0.04 |
r = − 0.5 p value < 0.0001 |
r = − 0.2 p value = 0.02 |
| PD-1+CD4+ (%) |
r = 0.2 p value = 0.03 |
r = 0.6 p value < 0.0001 |
r = 0.3 p value = 0.004 |
r = 1 p < 0.0001 |
– |
r = 0.6 p value < 0.0001 |
r = − 0.2 p value = 0.04 |
r = − 0.5 p value < 0.0001 |
r = − 0.2 p value = 0.02 |
| PD-1+CD8+ (%) |
r = − 0.02 p value = 0.4 |
r = 0.4 p value < 0.0001 |
r = 0.3 p value = 0.01 |
r = 0.6 p value < 0.0001 |
r = 0.6 p value < 0.0001 |
– |
r = − 0.3 p value = 0.007 |
r = − 0.4 p value = 0.001 |
r = − 0.2 p value = 0.02 |
| CCR5+CD19+ (%) |
r = − 0.1 p value = 0.2 |
r = − 0.04 p value = 0.4 |
r = 0.17 p value = 0.07 |
r = − 0.2 p value = 0.04 |
r = − 0.2 p value = 0.04 |
r = − 0.3 p value = 0.007 |
– |
r = − 0.06 p value = 0.3 |
r = − 0.2 p value = 0.02 |
| CCR5+CD4+(%) |
r = − 0.2 p value = 0.01 |
r = − 0.2 p value = 0.02 |
r = − 0.1 p value 0.2 |
r = − 0.5 p value < 0.0001 |
r = − 0.5 p value < 0.0001 |
r = − 0.4 p value = 0.01 |
r = − 0.06 p value = 0.3 |
– |
r = − 0.08 p value = 0.2 |
| CCR5+CD8+ (%) |
r = 0.2 p value = 0.04 |
r = − 0.4 p value < 0.0001 |
r = − 0.3 p value = 0.004 |
r = − 0.2 p value = 0.02 |
r = − 0.2 p value = 0.02 |
r = − 0.2 p value = 0.02 |
r = − 0.2 p value = 0.02 |
r = 0.08 p value = 0.2 |
– |
Pearson correlation, r correlation coefficient, bold r and p values indicate significance (p < 0.05)