Table 3.
Patient distribution around the cutoffs identified for immune biomarker parameters in the two study arms
Immune biomarker | Cutoff value | SOC + Oregovomab arm (na/nb, %c) | SOC arm (na/nb, %c) | p valued |
---|---|---|---|---|
Change in the number of CA125-specific IFN-γ+CD8+ T lymphocytes/ml | ≥ 6.69x103 | 9/3, 75.0 | 4/11, 26.7 | 0.013 |
Number of MDSC4/ml | ≥ 137,300 | 10/13, 43.5 | 10/14, 41.7 | n.s. |
NMLR | ≥ 4.388 | 10/26, 27.8 | 8/27, 22.9 | n.s. |
n.s.: not statistically significant
aNumber of patients with parameter value above cutoff
bNumber of patients with parameter value below cutoff
cPercentage of patients with parameter value above cutoff
dBy Fisher’s exact test