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. 2020 Jan 3;69(3):383–397. doi: 10.1007/s00262-019-02456-z

Table 3.

Patient distribution around the cutoffs identified for immune biomarker parameters in the two study arms

Immune biomarker Cutoff value SOC + Oregovomab arm (na/nb, %c) SOC arm (na/nb, %c) p valued
Change in the number of CA125-specific IFN-γ+CD8+ T lymphocytes/ml ≥ 6.69x103 9/3, 75.0 4/11, 26.7 0.013
Number of MDSC4/ml ≥ 137,300 10/13, 43.5 10/14, 41.7 n.s.
NMLR ≥ 4.388 10/26, 27.8 8/27, 22.9 n.s.

n.s.: not statistically significant

aNumber of patients with parameter value above cutoff

bNumber of patients with parameter value below cutoff

cPercentage of patients with parameter value above cutoff

dBy Fisher’s exact test