Table 1.
Total cohorta 520 |
LCK highb n = 23 |
Non-LCK high n = 497 | p value |
---|---|---|---|
Characteristic | |||
Age (median) | 40–78 (58) | 30–89 (59) | 0.837 |
ECOG performance | |||
0 | 4 | 69 | 0.633 |
1 | 3 | 72 | |
2 | 2 | 21 | |
3 | 0 | 4 | |
Unknown | 14 | 331 | |
Stage | |||
I | 1 | 15 | 0.134 |
II | 3 | 25 | |
IIIA, B | 3 | 28 | |
IIIC | 13 | 366 | |
IV | 3 | 80 | |
Unknown | 0 | 4 | |
Grade | |||
1 | 0 | 5 | 0.552 |
2 | 3 | 61 | |
3 | 19 | 419 | |
Unknown | 1 | 12 | |
Race/ethnicity | |||
Asian | 1 | 14 | 0.4696 |
Black | 0 | 23 | |
Hispanic | 1 | 7 | |
White | 20 | 433 | |
Other/unknown | 1 | 20 |
a520 patients included for a total of 535 samples available
bLC- high: expression > 1.86SD within TCGA ovarian serous cystadenocarcinoma study (TCGA, provisional)