TABLE 3.

Recognition of influenza virus proteins by CTL lines generated from the PBMC of two other donors

Virus strain used to infect autologous BLCL	% Specific 51Cr releasea
	Expt 1, 3F4, CD8+	Expt 2		Expt 3		Expt 4b
		3G11, CD8+	3E5, CD4+	3E9, CD4+	10E7, CD4+	124, CD8+	77, CD4+
Influenza virus A/PR/8/34	36			75	56	27	72
Vaccinia virus HA	52c					−6	−4
Vaccinia virus M1	−2			0	66
Vaccinia virus M2	−10					69	1
Vaccinia virus NA	0			59	2	0	2
Vaccinia virus NP		65	65			−2	0
Vaccinia virus NP aa 1–168		−2	−2
Vaccinia virus NP aa 147–315		1	33
Vaccinia virus NP aa 296–498		67	−6
Vaccinia virus PA				0	0
Vaccinia virus PB1				−1	−1
Vaccinia virus PB2				−3	−1	1	−1
Vaccinia virus NS1						3	74

^aThe E-T ratios was 10:1. The lysis of targets infected with wild-type vaccinia virus was subtracted from the lysis of targets infected with recombinant vaccinia viruses. 

^bThese T-cell lines were from donor 3; all others were from donor 2. 

^cLysis of the target cell demonstrating specific protein recognition by the cell line is underlined.