Table 4.
OS by PMN-MDSCs % and cytokine levels
| Variable | Median | 95% Confidence Interval | P | |
|---|---|---|---|---|
| Lower Bound | Upper Bound | |||
| PMN-MDSCs (%) | ||||
| ≤ 8 | 22.045 | 4.355 | 39.735 | 0.039 |
| > 8 | 9.265 | 0.000 | 18.81 | |
| IL-1β (pg/ml) | ||||
| ≤ 0.2339 | 14.883 | 7.563 | 22.203 | 0.923 |
| > 0.2339 | 11.565 | 3.856 | 19.273 | |
| IL-2 | ||||
| ≤ 1.575 | 12.879 | 3.380 | 22.378 | 0.557 |
| > 1.575 | 12.320 | 0.000 | 24.640 | |
| IL-27 (pg/ml) | ||||
| ≤ 194.8 | 16.427 | 8.466 | 24.389 | 0.645 |
| > 194.8 | 11.565 | 8.307 | 14.822 | |
| IL-29 (pg/ml) | ||||
| ≤ 36.74 | 11.926 | 5.459 | 18.394 | 0.441 |
| > 36.74 | 16.427 | 3.477 | 29.377 | |
| IL-1β + PMN-MDSCs | ||||
| ≤ 0.2339 ≤ 8 | 22.045 | 5.136 | 38.954 | 0.037 |
| ≤ 0.2339 > 8 | 8.509 | 0.000 | 19.542 | |
| > 0.2339 > 8 | 4.961 | 4.792 | 5.130 | |
| > 0.2339 ≤ 8 | 11.926 | 9.695 | 14.157 | |
| IL-2 + PMN-MDSCs | ||||
| ≤ 1.575 ≤ 8 | 36.205 | 2.357 | 70.054 | 0.113 |
| ≤ 1.575 > 8 | 6.505 | 0.722 | 12.288 | |
| > 1.575 > 8 | 8.509 | 0.000 | 32.529 | |
| > 1.575 ≤ 8 | 12.320 | 0.000 | 24.890 | |
| IL-27 + PMN-MDSCs | ||||
| ≤ 194.8 ≤ 8 | 22.045 | NR | NR | 0.009 |
| ≤ 194.8 > 8 | 15.573 | 0.000 | 39.115 | |
| > 194.8 > 8 | 4.895 | 0.925 | 8.865 | |
| > 194.8 ≤ 8 | 12.320 | 0.000 | 27.206 | |
| IL-29 + PMN-MDSCs | ||||
| ≤ 36.74 ≤ 8 | 22.045 | 1.425 | 42.665 | 0.049 |
| ≤ 36.74 > 8 | 5.092 | 0.000 | 11.290 | |
| > 36.74 > 8 | 16.427 | 0.000 | 41.046 | |
| > 36.74 ≤ 8 | 36.205 | 8.252 | 64.159 | |
Statistically significant are in bold