Table 2.
Median values (minimum and maximum given in brackets) for the 18F-FDG semi-quantitative and quantitative parameters before, after two cycles and after four cycles of ipilimumab in the CB group
| Parameter | First PET/ CT (baseline) | Second PET/CT (interim) | Third PET/CT (late) |
|---|---|---|---|
| SUVmean | 5.0 (1.8–13.3) | 5.0 (1.7–11.1) | 5.2 (1.4–19.0) |
| SUVmax | 8.1 (2.0-20.7) | 7.8 (2.1–24.7) | 8.5 (1.9–26.1) |
| K 1 | 0.17 (0.02–0.72) | 0.14 (0.03–0.55) | 0.15 (0.02–0.37) |
| k 3 | 0.09 (0.01–0.90) | 0.13 (0.02–0.41) | 0.11 (0.01–0.37) |
| Influx (Ki) | 0.02 (0.003–0.07) | 0.02 (0.01–0.08) | 0.03 (0.005–0.09) |
| FD | 1.20 (0.85–1.66) | 1.22 (0.90–1.30) | 1.21 (0.87–1.33) |
The values are derived from the hottest, melanoma-indicative lesions, up to a maximum of five lesions total. The units of parameters K1, k3 and influx are 1/min
SUVmean SUVmax and FD have no unit