Table 2.
Univariate and multivariate analysis for overall survival of all patients using the Cox proportional hazards model
| Characteristic | Parameter | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | p | HR | 95% CI | p | ||
| Age | < 60 | 1 | – | – | 1 | – | – |
| ≥ 60 | 1.25 | 1.01–1.54 | 0.037 | 1.34 | 1.08–1.67 | 0.008 | |
| Sex | Male | 1 | – | – | |||
| Female | 0.95 | 0.77–1.18 | 0.636 | ||||
| Tumor size (cm) | < 5 | 1 | – | – | 1 | – | – |
| ≥ 5 | 1.30 | 1.01–1.67 | 0.040 | 1.39 | 1.07–1.79 | 0.012 | |
| Tumor location | Head | 1 | – | – | |||
| Body and Tail | 1.12 | 0.91–1.39 | 0.285 | ||||
| Metastasis | Yes | 1 | – | – | 1 | – | – |
| No | 0.71 | 0.57–0.89 | 0.003 | 0.72 | 0.57–0.90 | 0.005 | |
| NLR | < 3.1 | 1 | – | – | 1 | – | – |
| ≥ 3.1 | 1.42 | 1.15–1.76 | < 0.001 | 1.48 | 1.19–1.83 | < 0.001 | |
| CD3−CD16+CD56+(NK) | < 20% | 1 | – | – | 1 | – | – |
| ≥ 20% | 1.41 | 1.14–1.73 | 0.001 | 1.45 | 1.17–1.79 | 0.001 | |
CI confidence interval, HR hazard ratio, NLR neutrophil-to-lymphocyte ratio