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. 2018 Mar 2;67(5):843–853. doi: 10.1007/s00262-018-2141-0

Table 1.

Characteristics of 25 patients with hepatic malignancies treated by selective internal radiotherapy

Female/male 5/20
Median age (range), years 73 (33–84)
Median administered activity (range), GBq 2.92 (1.01–6.42)
Median of target volume doses (range), Gy 119 (110–282)
Median lung dosea (range), Gy 6.45 (1–21.4)
Median pulmonary shunt (range) % 4.4 (1.3–28.1)
No. of treatment cycle
 1st 21
 2nd 3
 3rd 1
Primary tumor
 Liver 24
 CUP 1
Metastases
 Without 10
 Lungs 4
 Adrenal gland 2
 Bones 2
 Pancreas 1
 Stomach 1
 Other 5
Without/with bone metastases 23/2
Child–Pugh classa
 No liver cirrhosis = 0 3
 A = 1 21
Without/with chronic kidney disease 20/5
Without/with diabetes mellitus type II 12/13
ECOG performance status
 0 14
 1 9
 2 2
Without/with arterial hypertension 3/22
Without/with coronary artery disease 14/11
Laboratory-chemical values prior to SIRT
Glomerular filtration rate prior to therapyb
 < 90 mL/min/1.73 m2 20
 > 90 mL/min/1.73 m2 3
Quick value
 Within/below lower limit of normal 20/5
Serum creatinineb
 Within/above or below sex-dependent norm 14/9
Bilirubin total
 Within/above upper limit of normal 17/8
Bilirubin directa
 Within/above upper limit of normal 1/23
Albuminb
 Within/above upper limit of normal 22/1
Aspartate aminotransferaseb
 Within/above sex-dependent upper limit of normal 10/13
Alanine aminotransferaseb
 Within/above sex-dependent upper limit of normal 12/11
Alkaline phosphataseb
 Within/above sex-dependent upper limit of normal 8/15
Gamma-glutamyl transferaseb
 Within/above sex-dependent upper limit of normal 1/22
α-fetoprotein prior to SIRT
 < 10 IU/mL 12
 > 10 IU/mL 13
α-fetoprotein after SIRTc
 < 10 IU/mL 5
 > 10 IU/mL 17

CUP cancer of unknown primary, ECOG Eastern Cooperative Oncology Group

aOne unknown value

bTwo unknown values

cThree unknown values