Table 1.
Female/male | 5/20 |
Median age (range), years | 73 (33–84) |
Median administered activity (range), GBq | 2.92 (1.01–6.42) |
Median of target volume doses (range), Gy | 119 (110–282) |
Median lung dosea (range), Gy | 6.45 (1–21.4) |
Median pulmonary shunt (range) % | 4.4 (1.3–28.1) |
No. of treatment cycle | |
1st | 21 |
2nd | 3 |
3rd | 1 |
Primary tumor | |
Liver | 24 |
CUP | 1 |
Metastases | |
Without | 10 |
Lungs | 4 |
Adrenal gland | 2 |
Bones | 2 |
Pancreas | 1 |
Stomach | 1 |
Other | 5 |
Without/with bone metastases | 23/2 |
Child–Pugh classa | |
No liver cirrhosis = 0 | 3 |
A = 1 | 21 |
Without/with chronic kidney disease | 20/5 |
Without/with diabetes mellitus type II | 12/13 |
ECOG performance status | |
0 | 14 |
1 | 9 |
2 | 2 |
Without/with arterial hypertension | 3/22 |
Without/with coronary artery disease | 14/11 |
Laboratory-chemical values prior to SIRT | |
Glomerular filtration rate prior to therapyb | |
< 90 mL/min/1.73 m2 | 20 |
> 90 mL/min/1.73 m2 | 3 |
Quick value | |
Within/below lower limit of normal | 20/5 |
Serum creatinineb | |
Within/above or below sex-dependent norm | 14/9 |
Bilirubin total | |
Within/above upper limit of normal | 17/8 |
Bilirubin directa | |
Within/above upper limit of normal | 1/23 |
Albuminb | |
Within/above upper limit of normal | 22/1 |
Aspartate aminotransferaseb | |
Within/above sex-dependent upper limit of normal | 10/13 |
Alanine aminotransferaseb | |
Within/above sex-dependent upper limit of normal | 12/11 |
Alkaline phosphataseb | |
Within/above sex-dependent upper limit of normal | 8/15 |
Gamma-glutamyl transferaseb | |
Within/above sex-dependent upper limit of normal | 1/22 |
α-fetoprotein prior to SIRT | |
< 10 IU/mL | 12 |
> 10 IU/mL | 13 |
α-fetoprotein after SIRTc | |
< 10 IU/mL | 5 |
> 10 IU/mL | 17 |
CUP cancer of unknown primary, ECOG Eastern Cooperative Oncology Group
aOne unknown value
bTwo unknown values
cThree unknown values