Fig. 2.

CD73 in intrahepatic cholangiocellular carcinoma, BilIN, and extrahepatic bile duct carcinoma. a Cholangiocellular carcinoma showing positive neoplastic glands (arrows), showing a mild apical staining admixed with CD73 negative glands. b Cholangiocellular carcinoma showing moderate intensity homogeneous membranous staining. c Cholangiocellular carcinoma showing diffuse CD73 staining ranging from mild to strong in intensity. d BilIN showing very focal apical staining in dysplastic cells (arrows). e Bile duct carcinoma showing mild to moderate apical staining. f Bile duct carcinoma comprising an area with strong, membranous and cytoplasmic CD73 staining