Table 3.
Comparison of post-REP TIL derived from lung carcinoma and melanoma patients
| Lung TIL | Mel TIL | p values | |
|---|---|---|---|
| Fold expansion during REP | 1121 ± 349 | 1081 ± 493 | 0.76 |
| Final cell number (× 10E10) | 5.04 ± 1.57 | 4.86 ± 2.22 | 0.76 |
| CD8+CD3+ | 44 ± 30% | 59 ± 25% | < 0.001 |
| CD4+CD3+ | 56 ± 30% | 41 ± 25% | < 0.001 |
| CD28+CD3+ | 37 ± 19% | 58 ± 25% | 0.008 |
| 4-1BB+CD3+ | 6.5 ± 3.8% | 12 ± 15% | 0.140 |
| PD1+CD3+ | 57 ± 21% | 42 ± 25% | 0.096 |