Table 2.
PLAC1 localization in human cancer cell lines
| Cancer type | Cell line | Type of antibody | Immunogen | Staining technique | Reported localization | References |
|---|---|---|---|---|---|---|
| Breast | MCF-7 | pAb | aa:117–127 | IF | Cell membrane | [22] |
| BT- 549 | ||||||
| MCF-7 | mAb | aa:166–177 | ICC | Mainly cytoplasmic with some degree of cell membrane distribution | [66] | |
| MDA-MB-231 | ||||||
| T47D | ||||||
| Prostate | LNCap | Mainly cell membrane | ||||
| PC3 | Mainly cytoplasmic with some degree of cell membrane distribution | |||||
| Ovary | SKOV-3 | |||||
| Caov-4 | Mainly cell membrane | |||||
| Colon | SW 620 | pAb | Recombinant protein expressed in E. coli or synthetic peptides (p117–128 and p188–200) | ICC | Cytoplasmic | [30] |
pAb polyclonal antibody, mAb monoclonal antibody, IF immunofluorescence, ICC immunocytochemistry