Table 3.
PLAC1 localization in human cancer tissues using IHC
Cancer type | Type of antibody | Source of antibody | Immunogen | Reported localization | References |
---|---|---|---|---|---|
Breast | pAb | Squarix | 117–127 | Cell membrane | [22] |
Colon | pAb | Home-made | Recombinant protein expressed in E. coli or synthetic peptides (p117–128 and p188–200) | Cytoplasmic and cell membrane | [30] |
Colorectal carcinoma | pAb | Gifted by professor Michael Fant | NS | Nuclear and cytoplasmic (based on differentiation state) | [32] |
Prostate | pAb | Home-made | 166–177 | Cytoplasmic and cell membrane | [41] |
Pancreatic ductal adenocarcinoma | pAb | Abcam | NS | Cytoplasmic | [40] |
Primary gastric adenocarcinoma | pAb | NS | NS | Nuclear and cytoplasmic | [34] |
Hepatocellular Carcinoma | NS | Abcam | NS | Cytoplasmic and cell membrane | [29] |
pAb | Home-made | Mixture of 117–128 and 188–200 | NS (cytoplasmic based on the presented image) | [27] |
pAb polyclonal antibody, NS not specified