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. 2019 Apr 5;68(6):951–960. doi: 10.1007/s00262-019-02334-8

Table 2.

PD-L1 expression using immunohistochemistry with 22C3 and E1L3N clones

TC0 TC1 TC2 TC3 κ IC0 IC1 IC2 IC3 κ
E1L3N 68 4 1 1 0.831 60 12 2 0 0.818
22C3 69 3 1 1 60 11 3 0

PD-L1 positive tumor cells: < 1% (TC0), 1–4% (TC1), 5–49% (TC2) and > 50% (TC3)

PD-L1 positive immune cells: < 1% (IC0), 1–4% (IC1), 5–10% (IC2) and > 10% (IC3)