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. 2019 Apr 5;68(6):951–960. doi: 10.1007/s00262-019-02334-8

Table 6.

Cox multivariable analysis of factors associated with disease progression (nodal or visceral metastasis) in skin adnexal carcinomas

Hazard ratio 95% CI p
Univariable analysis
 PDL1 on tumor cells 4.0 1.1–15 0.0377
 PDL1 on immune cells 0.8 0.2–3 0.75
 CD8+ T-cell infiltrate 0.8 0.2–2.5 0.65
 Age 1.005 0.97–1.04 0.78
 T2 vs. T1 5.4 0.96–30 0.054
 T3 vs. T1 11.3 2.3–55 0.00275
 Vascular emboles 10.3 2.3–47 0.0026
Multivariable analysis
 PDL1 on tumor cells 4.1 0.6–29 0.15
 T2 vs. T1 6.7 1.1–43 0.044
 T3 vs. T1 10.0 1.8–57 0.009
 Vascular emboles 1.9 0.2–15 0.55

Bold values indicate statistically significant findings