Table 1.
Characteristics of allo-SCT patients used for MiHA T cell expansion assays
| Pt | Disease | MiHA T cell response | Sample date (months) | DLI prior to sample date | % MiHA-specific CD8+ T cells |
|---|---|---|---|---|---|
| 1 | MM | HA-1 | 20 post-SCT | Yes | 0.03 |
| 2 | NHL | HA-1 | 14 post-SCT | No | 0.02 |
| 3 | AML | LRH-1 | 12 post-SCT | No | 0.04 |
| 4 | CML-AP | LRH-1 | 13 post-SCT | Yes | 0.47 |
| 5 | AML | LRH-1 | 41 post-SCT | Yes | 0.02 |
Characteristics of patients with a hematological malignancy displaying MiHA-specific CD8+ T cell responses post-transplantation
Pt patient, AML acute myeloid leukemia, CML-AP chronic myeloid leukemia-accelerated phase, MM multiple myeloma, NHL non-Hodgkin’s lymphoma, SCT stem cell transplantation, DLI donor lymphocyte infusion, given at 4–10 months after allo-SCT