Table 2.

The effect of antibody response on survival

Censoring cutoff (months)	Hazard ratio [0.95 confidence interval] (P value)
	Effect of MVA response	Effect of 5T4 response
12	1.154 [0.940, 1.416] (0.17)	0.789 [0.634, 0.983] (0.035)
18	1.140 [0.964, 1.349] (0.13)	0.783 [0.656, 0.936] (0.0071)
24	1.060 [0.907, 1.239] (0.46)	0.789 [0.666, 0.934] (0.0059)

Response is defined as the natural logarithm of the ratio of antibody level at week 10 to that at baseline. A proportional hazards model for overall survival was used stratified by standard of care. The hazard ratios correspond to a doubling of the ratio of the antibody level at week 10 compared to baseline