Fig. 2.

Lymphocyte distribution in unaffected intestinal lamina propria (LP) and adenomas. The frequencies of CD4⁺, CD8⁺ and B220⁺ lymphocytes were determined by immunofluorescence in small intestinal and colon sections from APC^Min/+ and WT mice, and in APC^Min/+ intestinal adenomas. Frequencies of conventional CD4⁺ T cells (a), CD8⁺ T cells (b) and B220⁺ B cells (c) are expressed as the number of cells per mm². d Representative picture showing immunofluorescence staining of CD8⁺ T cells (green) in small intestinal section, displaying both adenoma and unaffected lamina propria. Symbols represent individual mice, and lines represent median. Mann–Whitney test was used for statistical analysis, **p < 0.01