Table 5.
Lymphoid subpopulation | Day +100 in % (CR vs. Non-CR before HSCT) | P values |
---|---|---|
CD3 IFNγ | 60 ± 7 vs. 40 ± 5 | NS (0.05) |
CD8 IFNγ | 46 ± 7 vs. 20 ± 6 | 0.02 |
CD3 CD45RO IFNγ | 82 ± 8 vs. 40 ± 5 | 0.007 |
IFNγ production in T-cells in patients who were in CR pre-SCT vs. patients who had detectable disease before transplantation was compared. The data depict the percentage of cytokine-positive cells in the respective T-cell subpopulation. Patients who were in CR pre-transplantation showed higher expressions of IFNγ, especially in CD8-positive and CD45RO-positive cells, on day +100 post-transplantation